The Irish Senior Cup round 2 fixtures are confirmed to take place on 16th October with the 6th November held as a provisional date.
Fixtures for the Irish Senior Cup are as follows:
Men’s Irish Senior Cup
| Round 1 | 2nd Oct’21 | ||
| Match # | Team | V | Team |
| 1 | Rathgar | Portrane | |
| 2 | Railway | Mossley | |
| 3 | Bandon | Kilkeel | |
| 4 | Clontarf | Cork Harlequins | |
| 5 | Cookstown | Instonians | |
| Round 2 | 16th Oct’21 | ||
| Match # | Team | V | Team |
| 6 | Winner 2 | Winner 5 | |
| 7 | Annadale | Pembroke | |
| 8 | Lisnagarvey | Winner 1 | |
| 9 | Banbridge | Monkstown | |
| 10 | Cork CofI | Winner 3 | |
| 11 | YMCA | UCD | |
| 12 | TRR | Corinthian | |
| 13 | Glenanne | Winner 4 |
| QF | 27th Nov ‘21 |
| SF | 27th Mar ‘22 |
Women’s Irish Senior Cup
| Round 1 | 2nd Oct’21 | ||
| Match # | Team | V | Team |
| 1 | Monkstown | UCC | |
| 2 | Ulster Elks | Ballymoney | |
| 3 | Banbridge | Ards | |
| 4 | Queens | Cork CofI | |
| 5 | DULHC | Corinthian | |
| Round 2 | 16th Oct’21 | ||
| Match # | Team | V | Team |
| 6 | Pegasus | Winner 2 | |
| 7 | Winner 4 | Winner 1 | |
| 8 | Glenanne | Winner 3 | |
| 9 | Cork Harlequins | Pembroke | |
| 10 | Lisnagarvey | Muckross | |
| 11 | Catholic Institute | Winner 5 | |
| 12 | UCD | Old Alex | |
| 13 | Railway | Loreto |
| QF | 27th Nov ‘21 |
| SF | 27th Mar ‘22 |